Category A Drugs: Human and animal studies show no risk to the fetus.
Take ‘em: Prenatal vitamins, folic acid
Category B Drugs: Animal studies have shown an adverse effect but human studies demonstrate no risk.
You’re safe with: Azelaic acid, prednisone
Category C Drugs: Animal studies have shown an adverse effect. No adequate human studies have been performed but benefits outweigh risks*.
You’re safe with: Tretinoin, topical retinoids
Category D Drugs: Evidence exists of human fetal risk but potential benefits outweigh risks.
You’re safe with: Tetracycline
Category X Drugs: Animal and human studies demonstrate fetal abnormalities. Risks outweigh any potential benefits.
Avoid It: Isotretinoin, thalidomide
*Most drugs are classified as Category C as a general precaution